AKH STUDY 2017
PROFERTIL® female is significantly superior to folic acid in terms of improvement of fertilization rate and embryo quality
53.85% higher pregnancy rate with PROFERTIL® female
Nouri K, et al. Gynecol Obstet Invest. 2017;82(1):8-14.
Prospective, randomized pilot study, n= 100, minimum 28 days PROFERTIL® female prior to ovarian hyperstimulation, vs. folic acid 400 μg
Number of patients
n = 100
(PROFERTIL® female group
n = 50; Control group n = 50)
Study design
Open single-center prospective randomized controlled pilot trial
Number of patients: 100
Clinical study to investigate the formulation of PROFERTIL® female
The Impact of a Standardized Oral Multinutrient Supplementation on Embryo Quality in in vitro Fertilization/Intracytoplasmic Sperm Injection: A Prospective Randomized Trial
Study objectives
Primary objective of this pilot study was to determine the effect of PROfertil® female (compared to 400 mcg of folic acid) in women undergoing IVF in terms of embryo quality.
As a secondary objective of the study, the clinical pregnancy rate was evaluated.
Outcome parameters
- Embryo quality on day 3 after oocyte retrieval (good quality vs. poor quality) and
- Clinical pregnancy rate.
*Nouri K. et al., Gynecol Obstet Invest. 2017;82(1):8-14.
